Catechol oxidase activity of di-Cu2+-substituted aminopeptidase from Streptomyces griseus.

نویسندگان

  • Giordano F Z da Silva
  • Li-June Ming
چکیده

Streptomyces griseus aminopeptidase exhibits activities toward the hydrolyses of peptides and bis(p-nitrophenyl)phosphate (40 billion fold) and catechol oxidation reported herein with catalytic efficiency (kcat/Km) only about 10 times smaller than that of gypsywort catechol oxidase. The multifunctionality of this enzyme suggests that it is a unique system for further exploration of protein structure and function and a template for design of enzymes of diverse activities.

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عنوان ژورنال:
  • Journal of the American Chemical Society

دوره 127 47  شماره 

صفحات  -

تاریخ انتشار 2005